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1.
Medicine (Baltimore) ; 98(17): e15388, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-31027132

RESUMO

RATIONALE: Chondrosarcoma is a malignant mesenchymal tumor originating from cartilage. The pelvis, ribs, femur, and humerus are the most frequently affected sites, and scapula involvement is relatively rare. The aim of the present study was to report a case of chondrosarcoma in the scapula. PATIENT CONCERNS: A 42-year-old woman presented with a 3-month history of a painful mass in the right scapula. DIAGNOSES AND INTERVENTION: The patient underwent tumor resection. The post-operative pathological diagnosis was scapula chondrosarcoma. OUTCOMES: Following resection, the patient continued to receive routine follow-up care. There was no recurrence or tumor metastasis at a follow-up of 5 years. CONCLUSIONS: Surgery remains the primary therapy for chondrosarcoma. One of the greatest challenges in the management of chondrosarcoma is to accurately assess tumor grade before surgical intervention. Chemotherapy and radiotherapy have been applied without success. Chemo- and radioresistance have been examined beyond classic phenotypic properties to identify more efficient therapeutic strategies. Therefore, development of future novel therapies is contingent upon elucidating the molecular mechanisms of chondrosarcoma.


Assuntos
Neoplasias Ósseas/diagnóstico , Condrossarcoma/diagnóstico , Escápula , Adulto , Neoplasias Ósseas/patologia , Neoplasias Ósseas/cirurgia , Condrossarcoma/patologia , Condrossarcoma/cirurgia , Diagnóstico Diferencial , Feminino , Humanos , Escápula/patologia , Escápula/cirurgia
2.
Medicine (Baltimore) ; 96(48): e8962, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-29310397

RESUMO

RATIONALE: Desmoplastic fibroma (DF) is a rare, locally invasive but benign bone tumor. It represents one of the rarest bone diseases, with an incidence of only 0.11% of all primary bone tumors. PATIENT CONCERNS: Herein, a case of massive and unusual DF, with simultaneous involvement of ilium and ischium, is described. A 29-year-old man suffered minor pain in his right hip for 2 years. It worsened after sudden movements, which prevented him from walking normally. Physical examination showed a limitation when the right hip was flexed and a percussion pain on the hip region. A medical imaging examination showed that the right ilium and ischium had a massive bone lesion. The top of acetabular had very little bone left and a fracture was likely at any time. No prominent body weight loss was noted, because there was no extensive invasion to the adjacent soft tissue. DIAGNOSES: DF of the Ilium and Ischium. INTERVENTIONS: The patient underwent a surgery involving curettage and grafting to maintain the stability of the pelvis. OUTCOMES: The definitive pathological diagnosis was DF, without evidence of malignancy. The postoperative recovery course at 3-month follow-up was uneventful. LESSONS: To the authors' knowledge, such a massive DF involving both ilium and ischium has been rarely reported. Young patients require appropriate and timely treatment modalities.


Assuntos
Neoplasias Ósseas/cirurgia , Fibroma Desmoplásico/cirurgia , Ílio/cirurgia , Ísquio/cirurgia , Adulto , Neoplasias Ósseas/diagnóstico por imagem , Neoplasias Ósseas/patologia , Curetagem , Fibroma Desmoplásico/diagnóstico por imagem , Fibroma Desmoplásico/patologia , Humanos , Ílio/diagnóstico por imagem , Ílio/patologia , Ísquio/diagnóstico por imagem , Ísquio/patologia , Masculino , Transplante de Tecidos
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